Celebrex is a brand of the prescription pain medication, belonging to the COX-2 inhibitor class of drugs, the non-steroidal anti-inflammatory drugs. The active ingredient present in Celebrex is celecoxib. Celebrex works by decreasing inflammation, which often is a major part of arthritis, neck pain and back pain. Celebrex is also approved for the treatment of osteoarthritis, rheumatoid arthritis common in adults, acute pain in adults and painful menstrual cramps and acute pain in adults.


An overdose of Celebrex can result in tiredness, weakness, nausea and vomiting, gastrointestinal bleeding, and abdominal pain. In not too common cases, a large overdose of Celebrex can result in kidney failure, high blood pressure, difficulty in breathing and at worst a coma. Overdose in case, call a poison center or 911. Take Celebrex as exactly prescribed by your doctor. Don’t increase or decrease the dosage. In case you miss a dose of Celebrex, administer it as soon as you remember. However if it is almost time for your next dose, skip the missed dose and continue with your regular dose. Do not double your dose to make up for the one you missed.


Patients who are allergic to celecoxib or any other ingredients of Celebrex should not take Celebrex. Likewise, patients who are allergic to sulfonamide type drugs should not take Celebrex. Based on your medical history, your doctor will deduce the lowest dose of Celebrex that works just for you. Celebrex should be taken once or twice a day, with or without food. However, if you’re being prescribed large doses, you may need to take the doses with food. Administer the medication at the same time daily. Children or adults who are not okay with swallowing capsules should open the capsule and mix the content with a teaspoon of Applesauce and take immediately.


Recent findings have shown Celebrex being effective for cancer treatment. Currently, it is uncertain whether the blocking of COX-2 by Celebrex may be a useful directive in the treatment of cancer. However, studies have also revealed that celecoxib may interact with other cell components in the body aside from the intended target, COX. This result contradicted the initial belief that Celebrex exerts primarily its anticancer effects through blocking of COX. Further studies brought to knowledge that although the anti-inflammatory properties of Celebrex were linked to the blocking of COX, the drug’s anticancer effect was not certain. One study conducted on malignant tumor cells revealed that Celebrex did shrink a part of these cells, but it also shown that this effect could also be accomplished with cancer cells without the enzyme COX.


Celebrex should be avoided in the last phase of pregnancy, starting at 30 weeks gestation, because it may cause premature closure of the ductus arteriosus. The risks should be weighed against the benefits.

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